Bibliography of synthesis documents on selected coastal ocean topics

This compilation of references to works which synthesize information on coastal topics is intended to be useful to resource managers in decision making processes. However, the utility must be understand in terms of its limited coverage. The bibliography is not inclusive of all the published materials on the topics selected. Coverage is clearly defined in the following paragraph. The time span of the bibliography is limited to references that were published from I983 to 1993, except for a last-minute addition of a few 1994 publications. All searches were done in mid- to late-1993. The bibliography was compiled from searches done on the following DIALOG electronic databases: Aquatic Sciences and Fisheries Abstracts, BlOSlS Previews, Dissertation Abstracts Online, Life Sciences Collection, NTlS (National Technical lnformation Service), Oceanic Abstracts, Pollution Abstracts, SciSearch, and Water Resources Abstracts. In addition, two NOAA electronic datases were searched: the NOAA Library and lnformation Catalog and the NOAA Sea Grant Depository Database. Synthesis of information is not an ubiquitous term used in database development. In order to locate syntheses of required coastal topics, 89 search terms were used in combinations which required 10 searches from each file. From the nearly 6,000 citations which resulted from the electronic searches, the most appropriate were selected to produce this bibliography. The document was edited and indexed using Wordperfect software. When available, an abstract has been included. Every abstract was edited. The bibliography is subdivided into four main topics or sections: ecosystems, coastal water body conditions, natural disasters, and resource management. In the ecosystems section, emphasis is placed on organisms in their environment on the major coastlines of the U.S. In the second section, coastal water body conditions, the environment itself is emphasized. References were found for the Alaskan coast, but none were found for Hawaii. The third section, on natural disasters, emphasizes environmental impacts resulting from natural phenomena. Guidelines, planning and management reports, modelling documents, strategic and restoration plans, and environmental economics related to sustainability are included in the fourth section, resource management. Author, geographic, and subject indices indices are provided. The authors would like to thank Victor Omelczenko and Terry Seldon of the NOAA Sea Grant Office for access to and training on the NOAA Sea Grant Depository Database. We are grateful also to Dorothy Anderson, Philip Keavey, and Elizabeth Petersen who reviewed the draft document

Population analysis of the GLB1 gene in South Brazil

Infantile GM1 gangliosidosis is caused by the absence or reduction of lysosomal beta-galactosidase activity. Studies conducted in Brazil have indicated that it is one of the most frequent lysosomal storage disorders in the southern part of the country. To assess the incidence of this disorder, 390 blood donors were tested for the presence of two common mutations (1622–1627insG and R59H) in the GLB1 gene. Another group, consisting of 26 GM1 patients, and the blood donors were tested for the presence of two polymorphisms (R521C and S532G), in an attempt to elucidate whether there is a founder effect. The frequencies of the R59H and 1622–1627insG mutations among the GM1 patients studied were 19.2% and 38.5%, respectively. The frequency of polymorphism S532G was 16.7%, whereas R521C was not found in the patients. The overall frequency of either R59H or 1622–1627insG was 57.7% of the disease-causing alleles. This epidemiological study suggested a carrier frequency of 1:58. Seven different haplotypes were found. The 1622–1627insG mutation was not found to be linked to any polymorphism, whereas linkage disequilibrium was found for haplotype 2 (R59H, S532G) (p < 0.001). These data confirm the high incidence of GM1 gangliosidosis and the high frequency of two common mutations in southern Brazil

Use of Pro-Cite in the NOAA Central Library

pp. 177-18

Continual improvement in ventilator acquired pneumonia bundle compliance: A retrospective case matched review

Objectives: This study aimed to describe the population of people who acquired ventilator acquired pneumonia and determine the feasibility of a larger scale study to assess the degree to which bundle compliance reduces or even eliminates, the risk of ventilator acquired pneumonia. Research methodology/design: A retrospective matched case note review was conducted to scrutinise 10 VAP cases. Cases were matched with two controls for age, gender, APACHE score and number of ventilated days. Compliance with the VAP bundle was determined by extracting data on compliance from case notes. Binary logistic regression was used to calculate odds ratios with confidence intervals which were utilised to determine numbers needed for a larger study. Setting: A general intensive care unit within a 750 bedded district general hospital, serving a population of approximately 270,000 people in Scotland. Main outcome measure: The outcome variable of interest was ventilator acquired pneumonia and the independent variable was ventilator acquired pneumonia bundle compliance. Results: Binary logistic regression suggested that cases which did not receive the bundle reliably were more likely to develop ventilator acquired pneumonia (OR 1.33, confidence interval (CI) 0.28-6.30). Statistical results should be interpreted with caution due to the small sample size, which is demonstrated with the wide ranging confidence intervals (CIs). Conclusion: Wide confidence intervals enable only a cursory impression as to numbers that would be required for a full scale trial. Nonetheless, the effect size indicated in this paper contributes towards consideration as to numbers needed for future studie

The role of CD-ROM in library automation: application of the NOAA library and information service division "intelligent catalog" CD-ROM database

pp. 141-14

Déterminer la pondération de la consommation des ressources en chimiothérapie ambulatoire liée à la charge de travail des infirmières

Les programmes de cancérologie ontariens se sont fixés comme objectif de dispenser des soins infirmiers de haute qualité et des traitements sécuritaires à la fois pour les patients et pour le personnel. Dans le domaine de la santé, les contraintes financières inhérentes à la prestation des soins exigent que les mécanismes de financement rendent compte non seulement du coût des médicaments mais encore de facteurs tels que les coûts des ressources humaines en pharmacie et en soins infirmiers. Alors que certaines organisations ont élaboré des systèmes de classification des patients afin de mesurer l’intensité des soins infirmiers et la charge de travail des infirmières, ces systèmes s’appliquent principalement aux clientèles hospitalisées et présentent de nombreux défis tels que la nécessité pour les infirmières de documenter la charge de travail exigée par les soins à des fins de justification. Cet article a pour but de tracer les grandes lignes de la méthodologie et de l’implication des infirmières en vue d’élaborer une pondération de la consommation des ressources basée sur les protocoles pouvant être appliquée aux salles de chimiothérapie ambulatoire. La méthodologie inclut la détermination de la charge de travail reliée au temps dont les infirmières ont besoin pour préparer, conseiller et évaluer les patients et leur fournir l’enseignement requis ainsi que le temps nécessaire pour rassembler les fournitures, accéder aux lignes de perfusion, surveiller, gérer les effets indésirables, gérer les symptômes et documenter les soins. La pondération de la consommation des ressources fournit une meilleure mesure de la complexité des soins exigés par les patients atteints de cancer traités en milieu ambulatoire